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Concurrently, metabolites such as 3-hydroxykynurenine (3-OH-KYN), quinolinic acid, the kynurenine-to-tryptophan ratio, and 3-hydroxyanthranilic acid (3-OH-AA) were positively correlated with measures of glucose metabolism and insulin resistance: fasting blood glucose (FBG), fasting serum insulin (FSIns), and the homeostatic model assessment of insulin resistance (HOMA-IR)

J Diabetes Mellit 3:221

Depot heterogeneity remains a potential confounder (extremity lipedema vs

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Cys 2 ), cystine-free (Cys 2 -free), or cystine-free supplemented with GSH (750 M), CysGly (750 M), Fer-1 (10 M), or Trolox (100 M), and relative cell numbers were determined (n = 8 technical replicates from 2 independent experiments)